Pharma 4.0 is one of the big topics being discussed in the industry right now. Because of this, the ISPE SC Munich organized this and 3 following seminars to show how Pharma 4.0 is changing the industry.

After a brief introduction to ISPE and ISPE DACH EL by Zacharias Heck and Felix Desch, Chris Williams started with his presentation about „Challenges in Chromatographic Modelling”.

A major step in downstream processing is the chromatography with which antibodies and proteins in general can be purified. Modelling in this field helps to understand how changes of process parameters, like the concentration of salts or ligands, affect the binding equilibrium, retention volume and peak width. Through modeling, the goals of reducing costs and time and increasing or maintaining the quality can be achieved.

Chris Williams also makes clear the importance of the model interpretation and the comparison with experimental data.

The one-hour seminar then ended with a Q&A session including the participants.

With more than 60 international participants from industry and academia, the first seminar of the seminar series was a complete success. This is also reflected in the predominantly positive evaluation of the seminar.